Pro-Fibrotic CD26-Positive Fibroblasts Are Present in Greater Abundance in Breast Capsule Tissue of Irradiated Breasts

Mimi R. Borrelli, MBBS, MSc, BSc; Dre Irizzary, MD; Ronak A. Patel, BS; Dung Nguyen, MD; Arash Momeni, MD; Michael T. Longaker, MD; and Derrick C. Wan, MD

Aesthetic Surgery Journal 2020, Vol 40(4) 369–379

Background: Breast capsular contracture is a major problem following implant-based breast reconstruction, particularly in the setting of radiation therapy. Recent work has identified a fibrogenic fibroblast subpopulation characterized by CD26 surface marker expression.

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"I GIVE..."

Dan Mills, MD
Laguna Beach, CA
Life Insurance Policy

“I give because my mentor, Rex Peterson, once said, ‘We should give back in the way that someone has given to us.’ My chosen profession has been good to me and by providing a gift to ASERF I am able to give back in a way that is long lasting and benefits our specialty as a whole.”