Comparative Analysis of Cytokines of Tumor Cell Lines, Malignant and Benign Effusions Around Breast Implants

Marshall E. Kadin, MD; John Morgan, PhD; Nick Kouttab, PhD; Haiying Xu, BS; William P. Adams Jr MD; Caroline Glicksman, MD; Patricia McGuire, MD; David Sieber, MD; Alan L. Epstein, MD, PhD; Roberto N. Miranda, MD; and Mark W. Clemens, MD

Aesthetic Surgery Journal 2019, 1–8

Background: More than 700 women have developed an anaplastic large T cell lymphoma (ALCL) surrounding textured surface breast implants, termed breast implant–associated ALCL (BIA-ALCL). Most patients with BIA-ALCL present with an accumulation of fluid (delayed seroma) around the implant. However, benign seromas without malignant cells complicating scar contracture, implant rupture, trauma, infection, and other causes are more common. For proper patient management and to avoid unnecessary surgery, a simple diagnostic test to identify malignant seromas is desirable.

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"I GIVE..."

Bahman Guyuron, MD
Lyndhurst, OH

“I give because plastic surgery is my passion and my business and the scientific studies supported through donations to ASERF work like Research and Development arm of any business; produce new and efficacious procedures and more importantly, assure patient safety”