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Pilot study to identify a genetic predisposition to BIA-ALCL Print

The ASERF Scientific Research Committee and Board of Directors are pleased to announce the following grant award:

Researcher: Terence Myckatyn, MD

Grant Award: ASERF Interim Grant

Amount Awarded: $24,736.00

Project Name: Pilot study to identify a genetic predisposition to BIA-ALCL

Project Summary:

Specific Goal. To characterize somatic and germline mutations in a cohort of women who received en bloc capsulectomies for breast implant associated-anaplastic large cell lymphoma (BIA-ALCL) using whole exome sequencing (WES) and whole genome sequencing (WGS) approaches. Importantly, we already have tissue and blood for all the BIA-ALCL patients we propose to study in this proposal. These specimens are available for immediate analysis. We can have data in less than 6 months from initiation of funding.

Hypothesis. WGS of the capsulectomies containing BIA-ALCL and matched normals will identify genetic alterations that help better understand the somatic and germline drivers of this disease.  

 
Understanding Breast Implant Illness Print

The ASERF Scientific Research Committee and Board of Directors are pleased to announce the following grant award:

Researcher: Jill Newby, PhD

Grant Award: ASERF Interim Grant

Amount Awarded: $20,000.00

Project Name: Understanding Breast Implant Illness

Project Summary:

Breast implant illness (BII) is a new term used to describe a myriad of symptoms that are proposed to be caused by breast implant (Magnusson et al. 2019); however, to date no scientific information has confirmed this, and there is no diagnostic test to make the diagnosis.
The ultimate goal of this project is to better understand the nature and causes of Breast Implant Illness, so that it can be: prevented (in women without symptoms), or treated and cured (in women with symptoms).
This project also aims to better understand the role of psychological/behavioral factors in perpetuating the distress linked to unexplained symptoms after implant surgery.

 
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