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The Aesthetic Surgery Education and Research Foundation

Silicone occlusive treatment of hypertrophic scar in the rabbit model Print

Alexandrina S. Saulis, Jerome D. Chao, Alvin Telser, Jon E. Mogford, Thomas A. Mustoe
Aesthetic Surgery Journal
March 2002 (Vol. 22, Issue 2, Pages 147-153)


Background

Hypertrophic scar formation at sites of healed cutaneous injury often produces functional and esthetic deficits. Treatments have been limited in part by a lack of understanding of scar etiology and the lack of animal models of hypertrophic scarring. Silicone dressing is reported to provide positive outcomes with respect to a reduction in scar hypertrophy and an improvement in color differences, although the exact mechanism is unknown.

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