Comparative Analysis of Cytokines of Tumor Cell Lines, Malignant and Benign Effusions Around Breast Implants

Marshall E. Kadin, MD; John Morgan, PhD; Nick Kouttab, PhD; Haiying Xu, BS; William P. Adams Jr MD; Caroline Glicksman, MD; Patricia McGuire, MD; David Sieber, MD; Alan L. Epstein, MD, PhD; Roberto N. Miranda, MD; and Mark W. Clemens, MD

Aesthetic Surgery Journal 2019, 1–8

Background: More than 700 women have developed an anaplastic large T cell lymphoma (ALCL) surrounding textured surface breast implants, termed breast implant–associated ALCL (BIA-ALCL). Most patients with BIA-ALCL present with an accumulation of fluid (delayed seroma) around the implant. However, benign seromas without malignant cells complicating scar contracture, implant rupture, trauma, infection, and other causes are more common. For proper patient management and to avoid unnecessary surgery, a simple diagnostic test to identify malignant seromas is desirable.

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"I GIVE..."

Dan Mills, MD
Laguna Beach, CA
Life Insurance Policy

“I give because my mentor, Rex Peterson, once said, ‘We should give back in the way that someone has given to us.’ My chosen profession has been good to me and by providing a gift to ASERF I am able to give back in a way that is long lasting and benefits our specialty as a whole.”