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The Aesthetic Surgery Education and Research Foundation

CD30 Regulation of IL-13–STAT6 Pathway in Breast Implant–Associated Anaplastic Large Cell Lymphoma Print
Marshall E Kadin, MD, John Morgan, PhD, Wei Wei, PhD, Zhihui Song, PhD, Yibin Yang, PhD

Aesthetic Surgery Journal, Volume 43, Issue 2, February 2023, Pages 137–146

Background: Breast implant–associated anaplastic large cell lymphoma (BIA-ALCL) is a rare, usually indolent CD30+ T-cell lymphoma with tumor cells, often surrounded by eosinophils, expressing IL-13 and pSTAT6.

Objectives: The aim of this study was to understand the unique tumor pathology and growth regulation of BIA-ALCL, leading to potential targeted therapies.

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