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Impact on ADMs on Biofilms Around Breast Implants

Researcher: Terry Myckatyn, MD

Grant Award: ASERF Interim Grant

Amount Awarded: $52,900

Project Name: Impact on ADMs on Biofilms Around Breast Implants
Project Summary: The proposed study will evaluate the problem of capsular contracture in aesthetic breast surgery. Importantly, a cellular dermal matrices are being touted for their utility in revision aesthetic breast surgery and for their ability to limit capsular contracture. Claims related to reduced capsular contractures are based on modest animal data, and a scant few qualitative comments in the literature.
The goal is to establish whether a cellular dermal matrices impact periprosthetic biolfilm formation-a leading culprit in the putative mechanism for capsular contracture.

Effects of facial topical lidocaine on serum levels of lidocaine and MEG-X

Researcher: Jeffrey M. Kenkel, MD

Grant Award: ASERF Interim Grant

Amount Awarded: $28,874

Project Name: Effects of facial topical lidocaine on serum levels of lidocaine and MEG-X

Project Summary: Topical lidocaine is applied liberally in clinics and spas throughout the world. Despite this, there is little to no data describing the safe doses, toxicity, and clinical guidelines regarding the topical use of lidocaine, particularly in a highly vascularized area such as the face. The primary purpose is to examine the metabolism of 4% topical lidocaine (LMX-4) to determine peak serum levels, and common clinical treatment variables affecting absorption, as a means of increasing patient safety.

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