Marshall E Kadin, MD, John Morgan, PhD, Haiying Xu, BS, Caroline Glicksman, MD, David Sieber, MD, William P Adams, Jr, MD, Pat McGuire, MD, Mark W Clemens, MD, Archana Thakur, PhD, Lawrence G Lum, MD, DSc
Aesthetic Surgery Journal, sjaa302
Background: Granzyme B (GrB) is a serine protease secreted, along with pore-forming perforin, by cytotoxic lymphocytes to mediate apoptosis in target cells. GrB has been detected in tumor cells associated with systemic and breast implant–associated anaplastic large cell lymphoma (BIA-ALCL) but its potential use for detection of early BIA-ALCL has not been fully investigated.
>> View on the Aesthetic Surgery Journal Website
|