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New Innovation For Projected Flap Design Print

The ASERF Scientific Research Committee and Board of Directors are pleased to announce the following grant award:

Researcher: Ross Sayadi, MD

Grant Award: ASERF Interim Grant

Amount Awarded: $6,670

Project Name: New Innovation For Projected Flap Design

Project Summary: Markings for planning incisions in plastic and reconstructive surgery are most commonly drawn free-hand and to the surgeon’s best estimate, leading to potential mistakes that can lead to increased procedure time and patient risk. We believe that using a projector to project images of prefabricated surgical markings will serve as a more effective method for surgical planning.

We aim to create a mobile application compatible with smart devices like the iPad, iPhone, or Android phones and tablets that will contain a database of existing designs for flap reconstruction. In addition, we plan on overlaying each flap on a thermal camera image of the local blood supply.

Surgeons will be able to choose a prefabricated flap and customize the parameters to a particular patient using touch technology on a smart device. The wireless image projector will then project the flap and thermal blood supply from the smart device onto the patient to serve as a template for efficient and reliable incision planning. Additionally, this technology can also serve as an educational tool for residents allowing them to gain mastery drawing flaps.

It is hypothesized that planning surgical incisions can be made more precise and reliable by using a projected image as a template for surgeons to draw markings.

 
Genomic Profiling to Understand the Pathogenesis of BIA-ALCL Print

The ASERF Scientific Research Committee and Board of Directors are pleased to announce the following grant award:

Researcher: Nandu Nair, MD

Grant Award: ASERF Interim Grant

Amount Awarded: $10,000

Project Name: Genomic Profiling to Understand the Pathogenesis of BIA-ALCL

Project Summary:
Hypothesis: We hypothesize that micro and nano-silica nanoparticles with polyurethane may differentially affect the induction of new biomarkers that can potentially influence the pathogenesis of BIA-ALCL. Accordingly, we propose following specific aim:  

Specific Aim: To study the comparative effect of nano, micro, and macro silica gel in combination with the polyurethane on global mRNA profiling in T-Cell. Hypothesis: a) silica and polyurethane is the basic implant materials; b) comparison of different sizes will reveal their physiological implications; c) The mRNA profiling will reveal novel yet unidentified molecular factors associated with the implant materials; d) identification of novel molecular markers specific to implant constituents may lead to better treatment approach in BIA-ALCL.

Significance: Currently more than 11 million women worldwide have breast implants and this number is continuously increasing. Recent reports of BIA-ALCL can be a significant health concern for women with implants. As such, examination of the molecular basis of BIA-ALCL may reveal specific biomarkers leading to better therapeutic approach.

 
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