Researcher: Jeffrey M. Kenkel, MD
Grant Award: ASERF Interim Grant
Amount Awarded: $28,874
Project Name: Effects of facial topical lidocaine on serum levels of lidocaine and MEG-X
Project Summary: Topical lidocaine is applied liberally in clinics and spas throughout the world. Despite this, there is little to no data describing the safe doses, toxicity, and clinical guidelines regarding the topical use of lidocaine, particularly in a highly vascularized area such as the face. The primary purpose is to examine the metabolism of 4% topical lidocaine (LMX-4) to determine peak serum levels, and common clinical treatment variables affecting absorption, as a means of increasing patient safety.